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butabarbital will minimize the level or result of fedratinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Influence of coadministering a strong CYP3A4 inducer with fedratinib has not been examined.butabarbital will lower the level or outcome of fosphenytoin by impacting hepatic enzyme CYP2C9/10 met